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KMID : 0378019630060120035
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New Medical Journal
1963 Volume.6 No. 12 p.35 ~ p.42
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A Study on the Salivary Excretion of Radioactive Iodine in Various Thyroid Function States
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Abstract
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The salivary excretion of radioactive iodine was studied in 87 cases of euthyroidism, 89 cases of hyperthyroidism and 24 cases of hypothyroidism. Twenty-four and forty-eight ´hours after the administration of tracer dose, radioactivities of saliva, and plasma protein bound iodine were measured and the results were expressed in salivary iodine percent dose per liter, saliva-plasma I131 ratio and saliva-FBI 131 ratio. The characteristics of this studies were compared with thyroid uptake of radioiodine and PBI131 :conversion ratio.
Salivary iodine percent dose per liter was (extremely ´decreased in hyperthyroid state and increased with the decrease of thyroid activity. F`,t´om these results, it was found that data from 24 hours saliva ´was more reliable to evaluate the thyroid function states, compared with that of 48 hours.
The results from saliva-plasma 1131 ratio and saliva-PBI131 ratio reflect also the various thyroid function states favourably, and the overlapping of the ranges between euthyroidism, and hypothyroidism was less frequently encountered in data ´from 48.hours saliva=plasma 1131 ratio.
All data obtained from salivary studies revealed the inverse relationship to the thyroid uptake of 1131 and may be satisfactory for the evaluation of thyroid function as a convenient method. For the screening of large population, salivary iodine percent dose .per liter of 24 hours is simple and rapid in its procedure and rather convenient to evaluate the diagnostic accuracy.
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